Synthesis, Crystal Structure and Absolute Configuration of (+)-O-Phenyl Cyclophosphorodiamidate

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The title compound, (+)-O-phenyl cyclophosphorodiamidate (C28H33N2O2P, Mr = 460.53), has been synthesized and characterized by 31P NMR, 1H NMR and elemental analysis. X-ray diffraction analysis at 273(2) K indicates that it belongs to orthorhombic system, space group P212121 with a = 11.518(4), b = 13.449(4), c = 16.539(5) ? V = 2562(1) 3, Z = 4, Dc = 1.194 g/cm3, F(000) = 984 and m(MoKa) = 0.134 mm-1. The structure parameters were refined by full-matrix least-squares on F2 to R = 0.0459 and wR = 0.0640. The flack x parameter is 0.03(10), and the absolute configuration of the phosphorus atom in the title compound is S. The title compound, (+) - O-phenyl cyclophosphorodiamidate (C28H33N2O2P, Mr = 460.53), has been synthesized and characterized by 31P NMR, 1H NMR and elemental analysis. X-ray diffraction analysis at 273 (2) K indicates that belongs to orthorhombic system, space group P212121 with a = 11.518 (4), b = 13.449 (4), c = 16.539 (5) V = 2562 (1) 3, Z = 4, Dc = 1.194 g / cm3, F 000) = 984 and m (MoKa) = 0.134 mm -1. The structure parameters were refined by full-matrix least-squares on F2 to R = 0.0459 and wR = 0.0640. The flack x parameter is 0.03 (10), and the absolute configuration of the phosphorus atom in the title compound is S.
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