消化道黏膜炎是化疗常见副反应,严重影响患者的生活质量和生存。在消化道黏膜炎发生、发展的病理过程中,肠道菌群、宿主、肠道微环境之间存在着复杂的相互作用,认识肠道菌群在此过程中发生的变化及其规律,有助于我们以肠道菌群为靶点,通过干预黏膜炎的病理反应过程,寻找预防和治疗放化疗相关黏膜炎和胃肠道不良反应的新方法。 Gastrointestinal mucositis is a common side effect of chemotherapy, seriously affecting the quality of life and survival of patients. In the pathogenesis and development of gastrointestinal mucositis, there is a complex interaction between intestinal microflora, host and intestine micro-environment, understanding of the changes and regularities of intestinal microflora in this process, there are Help us to gut bacteria as a target, through the intervention of mucositis pathological response process, looking for the prevention and treatment of radiotherapy and chemotherapy-related mucositis and gastrointestinal adverse reactions of the new method.