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目的评价南京市第三医院2010-2013年抗高血压药的使用情况及趋势,为临床合理用药和医院药品管理提供参考。方法对南京市第三医院2010-2013年抗高血压药的用药品种、年销售额(万元)、用药频度(DDDs)及日均药品费用(DDC)等进行统计和分析。结果 2010-2013年抗高血压药总DDDs和年销售额均逐年上升。钙拮抗剂、血管紧张素Ⅱ受体拮抗剂(ARBs)及β受体阻滞剂的销售金额一直排在前3位;DDDs一直排前3位的是钙拮抗剂、ARBs及利尿剂。单品种销售金额最高的是厄贝沙坦;单品种使用频度排前两位的是厄贝沙坦及苯磺酸氨氯地平;单品种DDC排序托拉塞米和乌拉地尔基本排在第1、2位。结论南京市第三医院抗高血压药物使用基本合理。
Objective To evaluate the use and trend of antihypertensives in the Third Hospital of Nanjing from 2010 to 2013 and provide references for clinical rational drug use and hospital drug management. Methods The data of antihypertensive drug varieties, annual sales (million), frequency of medication (DDDs) and daily average drug cost (DDC) of the Third Hospital of Nanjing from 2010 to 2013 were statistically analyzed. Results The total DDDs of anti-hypertensive drugs and annual sales in 2010-2013 increased year by year. Sales of calcium antagonists, angiotensin Ⅱ receptor antagonists (ARBs) and β-blockers were consistently ranked in the top 3; DDDs ranked the top 3 in terms of calcium antagonists, ARBs and diuretics. Irbesartan with the highest single-product sales amount; irbesartan and amlodipine besilate with the highest frequency of single-product use; single-product DDC with torsemide and urapidil Basic ranked first 1,2. Conclusion The third hospital in Nanjing antihypertensive drug use is reasonable.