论文部分内容阅读
业已证明,甲基汞是水俣病和Hunter-Russel′s病的病因。但是关于甲基汞的分布和排泄的机理,尤其是在细胞水平上,至今仍不十分清楚。许多学者从神经病理学的角度已有不少研究报导。可是,甲基汞对免疫系统作用的报导却很少。本文以小鼠急性甲基汞中毒实验来研究对免疫系统的作用。实验动物用S-10/Sn和ICR系雌性小鼠各30只。按Klein的方法自皮下注射0.2 mgCH_3HgOH/0.5 ml(相当于10 mgCH_3HgOH/kg体重),注射2～7次。对照组自皮下注入生理盐水。于最后一次注射后间隔一定时间,处死一定数量的小鼠。取出各脏器作组织学、组
Methylmercury has proven to be responsible for Minamata disease and Hunter-Russel’s disease. However, the mechanism of the distribution and excretion of methylmercury, especially at the cellular level, is not yet clear. Many scholars have reported many studies from the perspective of neuropathology. However, the role of methylmercury in the immune system is rarely reported. In this paper, mice with acute methylmercury poisoning experiments to study the role of the immune system. Experimental animals with S-10 / Sn and ICR female mice each 30. According to Klein’s method subcutaneous injection of 0.2 mgCH_3HgOH / 0.5 ml (equivalent to 10 mgCH_3HgOH / kg body weight), injected 2 to 7 times. The control group was injected subcutaneously with normal saline. A certain number of mice are sacrificed at intervals after the last injection. Remove the organs for histology, group