近年来新生儿败血症的发病率已明显下降,但此病仍然是新生儿发病和死亡的主要原因。在40年代磺胺药和青霉素发现以前,败血症的病死率高达90%,随着抗生素的不断发展、支持疗法的不断完善,新生儿败血症的病死率已大大下降,据1966～1978年的统计,病死率为26%。与此同时,致病菌也发生了明显的改变,B组溶血性链球菌(GBS)、 In recent years, the incidence of neonatal sepsis has decreased significantly, but the disease is still the main cause of neonatal morbidity and mortality. Before the discovery of sulfa drugs and penicillin in the 1940s, the mortality rate of sepsis was as high as 90%. With the continuous development of antibiotics and continuous improvement of supportive care, the mortality rate of neonatal sepsis has dropped significantly. According to statistics from 1966 to 1978, The rate is 26%. At the same time, pathogenic bacteria also changed obviously. Group B hemolytic streptococcus (GBS),