论文部分内容阅读
目的:探讨硫酸镁及硫酸镁联合硝苯地平治疗妊娠期高血压重度子痫前期的临床疗效。方法:选取2010年8月至2015年8月在重重庆市万州区妇幼保健院收治的妊娠期高血压重度子痫前期患者64例,随机均分为对照组和观察组,每组32例。对照组给予硫酸镁治疗,观察组在对照组的基础上给予硝苯地平治疗,比较两组临床疗效及不良反应。结果:观察组的总有效率为96.88%,明显高于对照组的75%,组间比较,差异具有统计学意义(P<0.05)。观察组的不良反应发生率为18.75%,对照组的为12.5%,组间比较,差异无统计学意义(P>0.05)。结论:硫酸镁联合硝苯地平治疗妊娠期高血压重度子痫前期的效果确切,优于硫酸镁。
Objective: To investigate the clinical effects of magnesium sulfate and magnesium sulfate combined with nifedipine in the treatment of severe preeclampsia of gestational hypertension. Methods: Totally 64 pregnant women with severe preeclampsia admitted to Wanzhou District Maternity and Child Care Hospital of Chongqing Municipality from August 2010 to August 2015 were randomly divided into control group and observation group, with 32 cases in each group. The control group was treated with magnesium sulfate. The observation group was treated with nifedipine on the basis of the control group. The clinical efficacy and adverse reactions of the two groups were compared. Results: The total effective rate of the observation group was 96.88%, which was significantly higher than that of the control group (75%). There was significant difference between the two groups (P <0.05). The incidence of adverse reactions in the observation group was 18.75% and that in the control group was 12.5%. There was no significant difference between the two groups (P> 0.05). Conclusion: Magnesium sulphate combined with nifedipine is effective in treating gestational hypertension with severe preeclampsia, which is superior to magnesium sulfate.