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癫痫是神经系统疾病中常见疾病,根据国内外流行病学调查,超过80%的癫痫患者生活在发展中国家。目前,我国有约900万癫痫患者,其中难治性癫痫(Intractable Epilepsy,IE)患者占所有癫痫患者的30%左右。频繁的癫痫发作严重伤害了患者的身体健康,致患者生活质量低下,死亡率显著增高。迄今为止,IE的发病机制尚不明确。近年研究发现,人类疱疹病毒6型(Human herpes virus 6,HHV-6)与IE的发生相关,文章就HHV-6在癫痫发病中的作用进行综述。
Epilepsy is a common disease in nervous system diseases. According to the epidemiological survey at home and abroad, more than 80% of epilepsy patients live in developing countries. At present, there are about 9 million epilepsy patients in our country, of which, patients with Intractable Epilepsy (IE) account for about 30% of all patients with epilepsy. Frequent epileptic seizures seriously hurt the health of patients, resulting in poor quality of life of patients, the mortality was significantly higher. So far, the pathogenesis of IE is not yet clear. Recent studies have found that human herpes virus 6 (HHV-6) is associated with the occurrence of IE, and the role of HHV-6 in epilepsy is reviewed.