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目的观察芬太尼联合丙泊酚在无痛人工流产(人流)术麻醉中的临床效果。方法 300例无痛人流术患者,根据麻醉方案不同分为对照组和观察组,各150例。对照组采用丙泊酚麻醉,观察组采用丙泊酚联合芬太尼麻醉,比较两组麻醉效果。结果观察组清醒时间为(4.1±1.2)min、离院时间为(15.3±3.7)d,显著短于对照组的(7.8±1.4)min、(27.3±5.3)d,差异有统计学意义(P<0.05);观察组丙泊酚使用量为(100.2±14.7)mg/kg,显著少于对照组的(117.4±16.4)mg/kg,差异有统计学意义(P<0.05)。观察组麻醉药物不良反应发生率为5.3%,显著低于对照组的13.3%,差异有统计学意义(P<0.05)。结论无痛人流术患者在丙泊酚麻醉基础上联合芬太尼麻醉效果理想,能减少丙泊酚使用剂量,术后不良反应发生率低,值得推广应用。
Objective To observe the clinical effect of fentanyl combined with propofol in painless abortion (abortion) anesthesia. Methods 300 cases of painless abortion patients, according to different anesthesia programs were divided into control group and observation group, 150 cases each. The control group received propofol anesthesia, the observation group received propofol combined with fentanyl anesthesia, anesthesia effects were compared between the two groups. Results The awake time was (4.1 ± 1.2) min in the observation group and (15.3 ± 3.7) days in the observation group, which was significantly shorter than that in the control group (7.8 ± 1.4) min and (27.3 ± 5.3) d, respectively P <0.05). The dosage of propofol in the observation group was (100.2 ± 14.7) mg / kg, which was significantly lower than that in the control group (117.4 ± 16.4) mg / kg, the difference was statistically significant (P <0.05). The adverse reaction rate of anesthetic drugs in the observation group was 5.3%, which was significantly lower than that in the control group (13.3%), the difference was statistically significant (P <0.05). Conclusion Painless abortion patients with propofol anesthesia combined with fentanyl anesthesia is ideal, can reduce the dose of propofol, the incidence of postoperative adverse reactions is low, it is worth promoting the application.