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胰岛素强化治疗可短期内将血糖控制至正常范围。对于1型糖尿病患者,从长远看,糖尿病强化治疗在一定程度上可减缓糖尿病视网膜病变(DR)的进展或减低其发生风险[1]。但治疗过程中有出现一过性DR加重的现象,且强化治疗组发生此现象的概率明显高于常规治疗组[2]。对于2型糖尿病患者,尚缺乏大样本前瞻性研究。本研究对并发早期DR的2型糖尿病患者行胰岛素强化治疗,并利用频域OCT观察胰岛素强化治疗对2型糖尿病患者黄斑形态的影响。
Intensive insulin therapy can be short-term blood glucose control to the normal range. In the long term, intensive treatment of type 1 diabetes may reduce the progression or reduce the risk of diabetic retinopathy (DR) to a certain extent [1]. However, there was a transient increase of DR in the course of treatment, and the probability of this phenomenon in the intensive treatment group was significantly higher than that in the conventional treatment group [2]. For type 2 diabetes, there is a lack of large sample prospective studies. In this study, patients with type 2 diabetes mellitus complicated with early DR were treated with insulin-enhanced therapy and the effect of insulin-enhanced therapy on macular morphology in patients with type 2 diabetes mellitus was observed using frequency-domain OCT.