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目的:总结胰腺实性假乳头状瘤(SPT)的临床特点及其治疗、预后。方法:回顾性分析69例SPT患者的临床表现、手术治疗、术后并发症及预后情况。结果:SPT位于胰头部24例(占34.8%)、胰颈部15例(占20.3%)、胰体尾部30例(占45.0%)。69例患者均行手术切除,无手术死亡。术后药物性肝功能衰竭1例、胰瘘9例、胃潴留3例,均保守治疗治愈。术后病理明显恶性者3例,其中1例术后26个月死于肿瘤脑转移,1例术后1年肝内及腹腔淋巴结复发、带瘤生存14个月,1例术后40个月无肿瘤复发。结论:SPT是一种低度恶性的胰腺肿瘤,预后相对良好,胰瘘是术后的主要并发症。
Objective: To summarize the clinical features, treatment and prognosis of solid pseudopapillary tumor of pancreas (SPT). Methods: A retrospective analysis of 69 cases of SPT patients with clinical manifestations, surgical treatment, postoperative complications and prognosis. Results: SPT was located in the head of pancreas in 24 cases (34.8%), in pancreatic neck in 15 cases (20.3%) and in pancreatic body in 30 cases (45.0%). All 69 patients underwent surgical resection without any surgical death. Postoperative drug-induced liver failure in 1 case, 9 cases of pancreatic fistula, gastric retention in 3 cases, were cured conservative treatment. One patient had brain metastases at 26 months after operation, one patient had recurrence of intrahepatic and abdominal lymph nodes at one year after operation, and the tumor survived for 14 months and one patient was 40 months after operation No tumor recurrence. Conclusion: SPT is a low-grade pancreatic tumor with a relatively good prognosis. Pancreatic fistula is a major complication after surgery.