十二指肠腺癌（DA）是一种少见的恶性肿瘤，约占全胃肠道癌的0.3％，全小肠癌的20％～45％。本病在1746年由Hamburger首先描述，至1974年世界文献报告不足700例。近十年来报告病例数大量增加，但基本治疗原则仍未解决。因病例相对较少，其自然病史和影响结果的因素、手术方式和 Duodenal adenocarcinoma (DA) is a rare malignancy that accounts for about 0.3% of total GI cancer and 20% to 45% of total small bowel cancer. The disease was first described by Hamburger in 1746, and by the end of 1974, less than 700 cases were reported in the world. The number of reported cases has increased substantially in the past decade, but the basic treatment principles have not yet been resolved. Due to the relatively small number of cases, the natural history and the factors affecting the outcome, the surgical approach and