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布洛芬片的工艺改进张绍鑫,王存良(河南省开封市永康制药厂,开封475300)布洛芬熔点较低,该片剂在制粒时,温度控制要求严格,属于比较难压制的片剂之一。目前国内大多数厂家多以淀粉浆制粒,填充也多以淀粉、糊精为主,压片时经常有粘冲现象,并且所压的布洛芬...
Process improvement of ibuprofen tablets Zhang Shaoxin, Wang Cunliang (Yongkang Pharmaceutical Factory, Kaifeng, Henan Province, Kaifeng 475300) The melting point of ibuprofen is relatively low. The tablets require strict temperature control during granulation and belong to the more difficult tablets one. At present, most domestic manufacturers mostly starch slurry granulation, filling is also mostly starch, dextrin-based, often sticky punch phenomenon, and the pressure of the ibuprofen ...