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目的:观察探讨米非司酮配伍米索前列醇药物终止早期妊娠的临床效果,总结治疗体会。方法:对2011年8月至2012年7月前来我院要求提前终止妊娠的100例孕8-14周患者随机分为观察组和对照组,对照组的患者单纯口服米索前列醇治疗,观察组的患者给予米非司酮配伍米索前列醇药物治疗,对两组患者的流产情况以及阴道出血情况进行对比观察。结果:观察组患者流产的总有效率明显优于对照组(P<0.05),观察组在流产过程中以及流产后的阴道出血量及出血时间较对照组而言也有明显区别(P<0.05),流产后子宫压痛、感染等并发症的发生率明显低于对照组。结论:米非司酮配伍米索前列醇药物流产疗法更有效,流产后并发症发生情况较少,操作简单,可有效促进患者尽快康复。
Objective: To observe the clinical efficacy of mifepristone and misoprostol in terminating early pregnancy and to summarize the experience of treatment. Methods: From August 2011 to July 2012, 100 pregnant women aged 8-14 weeks who came to our hospital for premature termination of pregnancy were randomly divided into observation group and control group. Patients in the control group were treated with oral misoprostol alone, Patients in the observation group were treated with mifepristone and misoprostol, and the abortion and vaginal bleeding in both groups were compared. Results: The total effective rate of abortion in the observation group was significantly better than that of the control group (P <0.05). There was also a significant difference between the observation group and the control group in the abortion and post-abortion vaginal bleeding and bleeding time (P <0.05) , Post-abortion uterine tenderness, infection and other complications was significantly lower than the control group. Conclusion: Mifepristone combined with misoprostol drug abortion therapy is more effective, less complications after abortion, simple operation, which can effectively promote the recovery of patients as soon as possible.