变形杆菌肺部感染一例

来源 :蚌埠医学院学报 | 被引量 : 0次 | 上传用户:zn19861225
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患者,男,57岁。肺结核病史30余年,糖尿病7年。于1987年9月11日因胸闷,呼吸困难、消瘦、咳痰带血而入院。体检:轻度贫血,消瘦,两肺可闻及少量湿性罗音,心率80次,心尖区可闻及Ⅱ级收缩期杂音。实验室检查:RBC 3.0×10~(12)/L,WBC 4.6×10~9/L,Hb 90g/L,中性76%,淋巴24%,嗜酸6%,单核2%。X线胸片提示右中下肺可见斑片状及团状密度不均阴影。入院后给予抗痨及止血消炎处理,症状无好转。反复查痰找抗酸杆菌均阴性,但在37℃沙保弱培养基里24h呈灰白色菌落,涂片为革兰氏阴性杆菌。转种普通平板上呈迁徒性扩散生长,尿素酶试验阳性,迅速分解葡萄糖,鉴定为变形杆菌。药物敏感试验:对庆大霉素、新青霉素 Patient, male, 57 years old. More than 30 years history of tuberculosis, diabetes, 7 years. On September 11, 1987 due to chest tightness, difficulty breathing, weight loss, sputum bloody and admitted to hospital. Physical examination: mild anemia, weight loss, two lungs can be heard and a small amount of wet rales, heart rate 80 times, apex area can be heard and Ⅱ systolic murmur. Laboratory tests: RBC 3.0 × 10-12 / L, WBC 4.6 × 10-9 / L, Hb 90g / L, neutral 76%, lymphoid 24%, eosinophil 6%, mononuclear 2%. X-ray showed right and left lung visible patches and clusters of uneven density shadow. Anti-tuberculosis and hemostatic anti-inflammatory treatment after admission, no improvement in symptoms. Repeated sputum to find acid-fast bacilli were negative, but at 37 ℃ Shabao weak medium in 24h pale gray colonies, smear Gram-negative bacilli. Transplants on a normal plate was apparently proliferative growth, urease test positive, rapid decomposition of glucose, identified as Proteus. Drug sensitivity test: on gentamicin, new penicillin
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