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目的探讨左西孟旦治疗老年心力衰竭患者的临床疗效。方法选取2014年3月至2016年3月辽宁省辽阳市辽阳石化总医院收治的90例老年心力衰竭患者作为研究对象,按随机数字表法将其分为对照组与观察组,各45例。对照组患者给予常规基础治疗,观察组患者在对照组基础上采用左西孟旦进行治疗,比较两组患者B型脑钠肽(BNP)、每搏心输出量(SV)、左心室射血分数(LVEF)、6 min步行试验、呼吸困难评分、全身症状评分及住院时间。结果治疗后,观察组患者的BNP水平明显低于对照组,差异有统计学意义(P<0.05);治疗后,观察组患者的SV明显低于对照组,LVEF明显高于对照组,差异均有统计学意义(均P<0.05);治疗后,观察组患者的6 min步行试验结果明显优于对照组,差异有统计学意义(P<0.05);治疗后,观察组患者的呼吸困难评分、全身症状评分均明显低于对照组,差异均有统计学意义(均P<0.05);观察组患者住院时间为(20±8)d,明显短于对照组的(25±9)d,差异有统计学意义(t=2.874,P<0.05)。结论在老年心力衰竭患者治疗中应用左西孟旦,能够有效改善患者心脏功能,缩短住院时间。
Objective To investigate the clinical efficacy of levosimendan in the treatment of elderly patients with heart failure. Methods From March 2014 to March 2016, 90 cases of elderly patients with heart failure treated in Liaoyang Petrochemical General Hospital of Liaoyang City, Liaoning Province were selected as the research objects. According to the random number table method, they were divided into control group and observation group, 45 cases in each group. Patients in the control group were given routine basic treatment. Patients in the observation group were treated with levosimendan on the basis of the control group. BNP, SV, left ventricular ejection fraction Score (LVEF), 6-min walking test, dyspnea score, generalized symptom score, and length of stay. Results After treatment, the level of BNP in the observation group was significantly lower than that in the control group (P <0.05). After treatment, the SV in the observation group was significantly lower than that in the control group, and the LVEF was significantly higher than that in the control group (P 0. 05). After treatment, the results of 6-min walking test in observation group were significantly better than those in control group (P 0. 05). After treatment, the patients in observation group had poor respiratory distress score (P <0.05). The hospitalization time in the observation group was (20 ± 8) d, which was significantly shorter than that in the control group (25 ± 9) d, and the score of the whole body symptom was significantly lower than that of the control group The difference was statistically significant (t = 2.874, P <0.05). Conclusion The application of levosimendan in the treatment of elderly patients with heart failure can effectively improve the cardiac function and shorten the hospital stay.