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系统性红斑狼疮(SLE)病人有50～80%发生肾脏病变,而狼疮性肾炎病人约有1/5会在10年内发展为终末期肾功能衰竭。曾有报告终末期肾功能衰竭的狼疮病人,大多数的 SLE 病情活动性是降低的,并经其它学者在进行血液透析的这类病人身上得到证实。但有报告提出用连续非卧床腹膜透析(CAPD)的狼疮病人,却更常会出现病情恶化。然而,迄今仍缺乏对这个问题的对比研究。本文对终末期肾功能衰蝎的 SLE 病人,比较了他们在透析前和透析期间的病情活动性,并比较了血液透析和 CAPD 两者治疗时的病程进展情况。病人和方法研究对象为55例有终末期肾功能衰竭的 SLE 病人,其中男13、女42例,平均年龄28±
Fifty to 80% of patients with systemic lupus erythematosus (SLE) develop nephropathy, and about one in five patients with lupus nephritis develop end-stage renal failure within 10 years. There have been reports of lupus patients with end-stage renal failure, most of which are reduced in mobility and confirmed by other scholars in such patients undergoing hemodialysis. However, it has been reported that patients with lupus in continuous ambulatory peritoneal dialysis (CAPD) develop more often than not. However, there is still no comparative study on this issue so far. In this paper, the patients with SLE with end-stage renal failure were compared for their disease activity before and during dialysis, and the course of the disease was compared between hemodialysis and CAPD. Patients and Methods The subjects were 55 SLE patients with end-stage renal failure, including 13 males and 42 females with an average age of 28 ±