硫酸钡作为消化道 X 线造影剂已有六十多年历史。近十余年来国外发展起来的双重造影技术,不但可提高一般疾病的诊断率,而且还可诊断早期癌症。双重造影用的硫酸钡制剂(以下称钡剂),必须具有高浓度、低粘度、粒子细、抗干扰等性能。为了提高双重造影的质量,我们对钡剂进行了研究。一、钡剂辅助剂的筛选欲制具有高浓度与低粘度性质的钡剂,必须选用合适的辅助剂。一般钡剂浓度愈高粘度愈大,浓度为100%(w/v,下同)时,已成为不易流动的半固体状态。因此,若能用辅助剂降低其粘度,则浓度可相对提高。 Barium sulfate as a digestive tract X-ray contrast agent has more than sixty years of history. Over the past decade or so developed dual-contrast imaging technology, not only can improve the diagnosis rate of general diseases, but also can diagnose early cancer. Double contrast barium sulfate preparations (hereinafter referred to as barium), must have high concentration, low viscosity, fine particles, anti-interference properties. In order to improve the quality of double contrast, we studied the barium. First, the screening of barium additives To make a barium with high concentration and low viscosity properties, we must choose the right adjuvant. Generally, the higher the concentration of barium, the greater the viscosity. At the concentration of 100% (w / v, the same below), it becomes a semi-solid state that is not easy to flow. Therefore, if the viscosity can be reduced with an adjuvant, the concentration can be relatively increased.