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膀胱过度活动症是一种以尿急症状为特征的症候群,常伴尿频和夜尿症状,可伴或不伴急迫性尿失禁。抗胆碱能药物抑制逼尿肌收缩是主要的治疗手段,但疗效不理想,且不良反应较大。膀胱镜下于膀胱内逼尿肌散在注射肉毒素A是一种新的治疗方法,但目前认为注射区域不应该包括三角区,以避免术后膀胱输尿管返流。为评价膀胱三角区注射肉毒素A治疗膀胱过度活动症的疗效及是否会引起膀胱输尿管返流,作者对12例临床诊断的膀胱过度活动症女性行膀胱内逼尿肌(包括膀胱三角区域)散在注射肉毒素A。纳入标准:对行为疗法、盆底肌训炼、药物治疗无效的非神经源性膀胱过度活动
Overactive bladder is a syndrome characterized by urinary symptoms, often associated with frequent urination and nocturia, with or without urge incontinence. Anticholinergic drugs inhibit detrusor contraction is the main treatment, but the effect is not satisfactory, and adverse reactions. Cystoscopy in the urinary bladder detrusor injection of botulinum toxin A is a new treatment, but at present it is thought that the injection area should not include the triangular area to avoid postoperative urinary vesicoureteral reflux. In order to assess the efficacy of injecting botulinum toxin A in the treatment of bladder overactive bladder in the trigone of the bladder and whether it will cause vesicoureteral reflux, 12 pairs of clinically diagnosed overactive bladder patients with bladder detrusor (including trigone area) Botox injection. Inclusion criteria: Non-neurogenic bladder over-activity on behavior therapy, pelvic floor muscle training, drug therapy