论文部分内容阅读
在《趋化因子研究进展──趋化因子家族》一文中，我们主要讨论了趋化因子家族的组成、结构特点及生物学作用。而有关趋化因子家族受体的研究亦日益深入，其中已克隆成功的受体有ＩＬ－８ＲＡ，ＩＬ－８ＲＢ及ＭＩＰ－１α／ＲＡＮＴＥＳ受体。此外在红细胞表面发现了趋化因子受体，并且有些病毒的产物亦发现与某些趋化因子有很高的同源性，人类的一些炎性及非炎性疾病与趋化因子的关系也非常密切，本文就这些方面的研究进展作一综述。
In the article “Progress in chemokine research - a family of chemokines”, we mainly discuss the composition, structural characteristics and biological roles of chemokine families. Studies on the family of chemokine receptors have also deepened. Among them, IL-8RA, IL-8RB and MIP-1α / RANTES receptors have been successfully cloned. In addition, chemokine receptors have been found on the surface of erythrocytes, and some virus products have also been found to have high homology with certain chemokines. The relationship between some inflammatory and non-inflammatory diseases in humans and chemokines Very close, this article reviews the progress of these aspects.