论文部分内容阅读
目的了解新疆维吾尔自治区、西藏自治区和云南省口岸和边境地区,中国健康儿童和入境外籍儿童肠道病毒(Enterovirus,EV)携带情况。方法在三个省(自治区,下同)口岸和边境地区,邀请<15岁中国籍健康儿童和入境的<15岁外籍儿童参加研究,经研究对象监护人知情同意后,由疾病预防控制中心专业人员调查研究对象的人口学特征、免疫史等信息,并采集粪便标本进行EV的分离和鉴定。结果采集312份外籍儿童粪便标本,非脊髓灰质炎(脊灰)(Non-polio)EV(NPEV)分离率为9.6%,三个省外籍儿童NPEV分离率差异有统计学意义(Χ2=12.71,P<0.01)。三个省共采集中国健康儿童粪便标本425份,分离出2株Ⅰ型脊灰疫苗株病毒和1株Ⅲ型疫苗衍生脊灰病毒,NPEV分离率为13.2%。结论动态监测健康儿童EV,作为急性弛缓性麻痹病例监测系统的有效补充,为维持无脊灰状态提供实验室依据。
Objective To understand the status of Enterovirus (EV) infection in healthy children and foreign children entering Xinjiang Uygur Autonomous Region, Tibet Autonomous Region and Yunnan Province at the ports and border areas. Methods Chinese children <15 years of age and foreign children <15 years old were invited to participate in the study at the ports and border areas of the three provinces (autonomous regions, the same below). After the informed consent of the guardian of the research object, the CDC professionals Demographic characteristics, immune history and other information were investigated, and stool specimens were collected for EV isolation and identification. Results A total of 312 foreign children stool samples were collected. The non-polio EV (NPEV) isolation rate was 9.6%. There was significant difference in the NPEV isolation rate among foreign children (Χ2 = 12.71, P <0.01). In the three provinces, a total of 425 stool samples were collected from healthy children in China. Two strains of poliovirus type I and one type III of vaccine-derived poliovirus were isolated. The NPEV isolation rate was 13.2%. Conclusion Dynamic monitoring of healthy children with EV, as an effective supplement to the surveillance system of acute flaccid paralysis cases, provides a laboratory basis for maintaining polio-free status.