肺气肿是一种临床上表现为进行性发展的不可逆气流受限 ,病理学上表现为肺部终末细支气管远端气腔出现异常持久的扩张 ,并伴有肺泡壁和细支气管的破坏而无明显纤维化的疾病[1 ] 。肺气肿由于患病人数多、死亡率高、社会经济负担重、不少国家的发病率仍不断上升 ,已成为一个重要 Emphysema is a clinically manifested as progressive development of irreversible airflow limited pathological manifestations of the lung distal bronchioles distal abnormal long-lasting expansion, and accompanied by the destruction of the alveolar wall and bronchioles Without obvious fibrosis disease [1]. Emphysema has become an important issue due to the large number of patients, high mortality rate, heavy social and economic burden and the rising incidence of many countries