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由于先天性心脏病(先心病)并发肺动脉高压(PAH)患者的死亡率和致残率均较高,人们重新审视了先心病并发PAH的流行病学特征及分类,并探索新的治疗手段,发掘新的能够反映PAH严重程度及预后的生物学标志物,为先心病并发PAH诊治水平的提高开辟了广阔的前景。
Due to the high mortality and morbidity of patients with congenital heart disease (CHD) complicated with pulmonary hypertension (PAH), the epidemiological features and classification of PAH in patients with congenital heart disease have been reexamined and new therapeutic approaches have been explored. The discovery of new biomarkers that can reflect the severity and prognosis of PAH has opened up broad prospects for the improvement of diagnosis and treatment of congenital heart disease complicated with PAH.