论文部分内容阅读
目的:探讨原发性肾脏滑膜肉瘤的临床表现及病理特点,诊断和治疗方法。方法:回顾性分析1例原发性肾脏滑膜肉瘤的诊治资料并复习国内外文献。结果:患者行根治性肾切除术。经镜下检查及免疫组化染色后,病理诊断考虑为原发性肾脏滑膜肉瘤,通过RT-PCR方法检测出SYT-SSX融合基因表达,确诊为原发性肾脏滑膜肉瘤。患者未行规律化疗,术后4个月局部复发,死亡。结论:原发性肾脏滑膜肉瘤临床上罕见,免疫组化染色对鉴别诊断有重要价值,检测SYT-SSX融合基因作为确诊所需最重要的检查。患者预后差。
Objective: To investigate the clinical manifestations, pathological features, diagnosis and treatment of primary renal synovial sarcoma. Methods: A retrospective analysis of 1 case of primary renal synovial sarcoma diagnosis and treatment of data and review of domestic and foreign literature. Results: The patients underwent radical nephrectomy. After microscopic examination and immunohistochemical staining, the pathological diagnosis was considered as primary renal synovial sarcoma. The expression of SYT-SSX fusion gene was detected by RT-PCR and confirmed as primary renal synovial sarcoma. Patients were not regular chemotherapy, 4 months after the local recurrence and death. Conclusions: Primary renal synovial sarcoma is clinically rare. Immunohistochemical staining is of great value in the differential diagnosis. Detection of SYT-SSX fusion gene is the most important examination for the diagnosis. Poor prognosis in patients.