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本文介绍一种豚鼠在体肠系膜下神经节(IMG)细胞内电活动的记录方法及用该方法所观察的初步结果。研究表明,这种方法较简便易行,能经常获得半小时至数小时之久稳定的、高质量的细胞内记录。在戊巴比妥钠浅麻醉条件下,肠系膜下神经节细胞95％具有自发的、不同步的快兴奋性突触电位活动,约52％的细胞达到阈值,引起0.2～12次/秒不均匀的自发放电。这种自发的紧张性突触电活动主要由胆碱能性突触前末梢释放递质所致。
This article describes a method of recording the electrical activity of guinea pigs in the subgingival ganglion (IMG) cells and the preliminary results observed with this method. Studies have shown that this method is simple and easy, and can often obtain stable, high quality intracellular recording for half an hour to several hours. In shallow sodium pentobarbital anesthesia conditions, 95% of mesenteric ganglion cells spontaneous, asynchronous fast excitatory synaptic potential activity, about 52% of the cells to a threshold, causing 0.2 to 12 times / s uneven Spontaneous discharge. This spontaneous tension-induced synaptic electrical activity is mainly caused by the release of neurotransmitters from the cholinergic presynaptic terminals.