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目的:探讨甲氨蝶呤联合米非司酮治疗宫外孕的临床疗效。方法:将2011年1月~2011年11月入我院治疗的30例宫外孕患者,随机分为联合组和对照组,其中联合组采用氨蝶呤联合米非司酮治疗,对照组采用米非司酮治疗,比较2组的疗效和治疗前后血β-人绒毛膜促性腺激素和盆腔包块的情况。结果:2组治疗后,联合组有14例治愈,治愈率高达93.33%,显著高于对照组的73.33%,P<0.05,2组治疗后,联合组患者血清β-HCG含量显著低于对照组,包块消失时间、腹痛消失时间和阴道停止流血时间均显著短于对照组,P<0.05。结论:甲氨蝶呤联合米非司酮治疗宫外孕的治愈率高,能明显降低β-HCG水平,缩短腹痛和包块消失时间。
Objective: To investigate the clinical efficacy of methotrexate combined with mifepristone in the treatment of ectopic pregnancy. Methods: 30 cases of ectopic pregnancy treated in our hospital from January 2011 to November 2011 were randomly divided into combined group and control group. The combination group was treated with methotrexate and mifepristone, while the control group was treated with mifepristone Cholesterol treatment, compared the efficacy of two groups and before and after treatment of blood β-human chorionic gonadotropin and pelvic mass situation. Results: In the two groups, 14 cases were cured in the combined group, the cure rate was as high as 93.33%, significantly higher than that in the control group (73.33%, P <0.05). After treatment, the serum β-HCG level in the combined group was significantly lower than that in the control group Group, the disappearance of mass, disappearance of abdominal pain and vaginal bleeding time were significantly shorter than the control group, P <0.05. Conclusion: Methotrexate combined with mifepristone in the treatment of ectopic pregnancy high cure rate, can significantly reduce the level of β-HCG, reduce abdominal pain and mass disappearance of time.