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目的研究肺炎支原体抗体滴度变化与肺炎支原体肺炎(MPP)病情严重程度的关系。方法回顾性分析2016年11月至2017年8月山西医科大学第一医院儿科68例MPP患儿的临床资料,分轻、重度两组,观察两组患儿的病情,并与支原体抗体滴度进行相关性分析。结果 (1)68例MPP患儿中,重症48例,轻症20例,重症组与轻症组临床资料结果显示,重症组WBC、CRP、中性百分比、PCT、ESR、LDH均高于轻症组(P<0.05)。(2)患儿病情轻重与支原体抗体滴度倒数之间相关性分析显示:二者呈正相关。结论随着患儿支原体抗体滴度的升高,患儿的病情也逐渐加重,所以检测MP抗体滴度可以早期判断患儿病情的严重程度,减少肺外并发症的发生。
Objective To study the relationship between the change of antibody titer of Mycoplasma pneumoniae and the severity of Mycoplasma pneumoniae pneumonia (MPP). Methods The clinical data of 68 children with MPP in pediatrics of the First Hospital of Shanxi Medical University from November 2016 to August 2017 were retrospectively analyzed. The patients in both groups were divided into mild and severe groups. The incidence of mycoplasma pneumoniae, Conduct correlation analysis. Results (1) Among the 68 MPP children, 48 cases were severe and 20 cases were mild. The clinical data of severe and mild group showed that the WBC, CRP, neutral percentage, PCT, ESR and LDH in severe group were higher than those in mild group Disease group (P <0.05). (2) Correlation analysis between the severity of illness and countdown of mycoplasma antibody showed that there was a positive correlation between them. Conclusion With the increase of titers of mycoplasma antibody in children, the condition of children is gradually aggravated. Therefore, the detection of MP antibody titers can early determine the severity of the disease in children and reduce the incidence of extrapulmonary complications.