本文通过低强度 Ｈｅ Ｎｅ 激光以能量密度分别为 １４３１ Ｊ／ｃｍ ２ （辐照 ５′）、２８６２ Ｊ／ｃｍ ２ （辐照 １０′）、５７２４ Ｊ／ｃｍ ２ （辐照 ２０′）１１４５２ Ｊ／ｃｍ ２ （辐照 ４０′）照射人体外周血后，检测其淋巴细胞染色体畸变率（ Ｃ Ａ），激光照射血样（能量密度由低到高）及未照射血样 Ｃ Ａ 分别平均为 ４２９‰、３９６‰、３８１‰、３５９‰、４１９‰， Ｘ２ 检验无显著差异（ Ｐ＞ ００５），说明低强度的 Ｈｅ Ｎｅ 激光辐照人体细胞对细胞染色体无致畸变效应。而且随着能量密度的增大，染色体的畸变率有降低的趋势，因此认为是低强度的 Ｈｅ Ｎｅ 激光促使细胞内分子的相互作用和能量转换，从而使染色体损伤的修复增强，其机理有待于进一步的研究。 In this paper, the low-intensity He Ne laser was used to measure the energy density of 1431 J / cm 2 (irradiation 5 ’), 2862 J / cm 2 (irradiation 10’) and 5724 J / cm 2 (C A), laser irradiation (low to high energy density) and non-irradiation blood sample C (C) were detected after irradiation of human peripheral blood with 114  52 J / cm 2 A were respectively 4.29 ‰, 3.96 ‰, 3.81 ‰, 3.59 ‰, 4.19 ‰. There was no significant difference between the two groups (P> 0.05), indicating that low intensity He Ne laser According to human cells on the chromosomes of cells without causing distortion. And as the energy density increases, the chromosome aberration rate tends to decrease, so it is considered that the low intensity He Ne laser can promote the interaction and energy conversion of intracellular molecules, so that the repair of chromosome damage is enhanced, and the mechanism remains to be Further research