198 4年 Lutjen等 [1] 创立了世界第 1例应用捐赠卵子体外受精胚胎移植技术 ,使一位卵巢早衰患者成功妊娠并分娩正常新生儿的记录。 1 987年 Ser-hal和 Craft[2 ]成功的运用简化的激素替代方案使受卵者妊娠并创造了延长生殖阶段的概念。我国第 1例卵巢早衰患者采用捐赠卵子体外 198 4 years Lutjen et al [1] created the world’s first case of donated egg fertilization by in vitro fertilization embryo transfer technology, so that a premature ovarian failure in pregnancy and childbirth normal newborn records. In 1987, Ser-hal and Craft [2] succeeded in using a simplified hormone replacement scheme to allow the recipient’s pregnancy and to create the concept of an extended reproductive stage. China’s first case of premature ovarian failure donated eggs in vitro