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目的：评价Ｇｄ－ＤＴＰＡ造影增强ＭＲＡ诊断脑膜瘤，特别是显示肿瘤血运情况的价值。材料与方法：４８例脑膜瘤患者行增强ＭＲＡ检查，其中２５例经手术病理证实，男８例，女１７例，男女之比为１２．３。年龄３６～７２岁，平均５４±１１岁。应用１．０Ｔ磁共振成像机（ＳｉｅｍｅｎｓＩｍｐａｃｔ），Ｇｄ－ＤＴＰＡ为磁显葡胺和／或马根维显，剂量０．１ｍｍｏｌ／ｋｇ，静脉团注后１０～１５分钟内行三维ＴＯＦ脑ＭＲＡ检查，以ＭＩＰ法重建图像。另外，１０例患者仅行平扫ＭＲＡ检查，作为对照组。结果：２５例患者显示２８个脑膜瘤，最小为１．２ｃｍ×１．２ｃｍ×１．４ｃｍ，最大达７．２ｃｍ×７．８ｃｍ×８．１ｃｍ，均有明显肿瘤染色。２７个肿瘤（９６％）主要由颈外动脉的分支供血，其中６个有“双重供血”。２５个肿瘤（８９．３％）显示引流静脉及其引流途径，２个肿瘤直接累及静脉窦。２１个肿瘤（７５％）显示脑内动脉及其分支有不同程度的移位。而对照组仅１个肿瘤显示轻度肿瘤染色，４个（４０％）显示脑内动脉及其分支的移位。结论：增强ＭＲＡ显示脑膜瘤的血运情况与术中所见相符，能代替Ｘ线脑血管造影行精确术前诊断，值得推广应用。
OBJECTIVE: To evaluate the value of Gd-DTPA contrast-enhanced MRA in diagnosing meningioma, especially the blood flow of tumors. Materials and Methods: Forty-eight patients with meningioma underwent enhanced MRA, of which 25 cases were confirmed by operation and pathology. There were 8 males and 17 females with a male to female ratio of 12.3. Age 36 to 72 years old, average 54 ± 11 years old. Using a 1.0T magnetic resonance imaging machine (Siemens Impact), Gd-DTPA for magnetic dextran and/or Magnevistin, at a dose of 0.1 mmol/kg, three-dimensional TOF brain MRA examination within 10 to 15 minutes after bolus injection to MIP Method to rebuild the image. In addition, 10 patients underwent only plain scan MRA examination as a control group. RESULTS: Twenty-five patients showed 28 meningiomas with a minimum of 1.2 cm x 1.2 cm x 1.4 cm and a maximum of 7.2 cm x 7.8 cm x 8.1 cm, all with marked tumor staining. Twenty-seven tumors (96%) were mainly supplied from the branches of the external carotid artery, of which 6 had “dual blood supply.” Twenty-five tumors (89.3%) showed drainage veins and their drainage routes, and two tumors directly involved venous sinuses. Twenty-one tumors (75%) showed varying degrees of intracerebral arterial and its branch displacement. In the control group, only 1 tumor showed mild tumor staining, and 4 (40%) showed displacement of the cerebral artery and its branches. Conclusion: The enhancement of MRA shows that the blood supply of meningioma is consistent with that seen during surgery. It can be used in place of X-ray cerebral angiography for accurate preoperative diagnosis. It is worthy of popularization and application.