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目的 对居家镇痛治疗的晚期癌性疼痛患者进行镇痛效果的观察和评估。方法 选择 5 12例经病理证实的晚期癌症患者 ,以世界卫生组织三阶梯止痛原则为指导 ,在家中镇痛药物为主 ,辅以其他麻醉技术和心理疏导进行综合镇痛治疗。镇痛效果采用数字分级法、生存质量评估和卡诺夫斯基功能状态评分评估。结果 5 12例患者中途退出 3例 ;4 97例药物镇痛有效 ,有效率97 1% ;出现顽固性疼痛 12例 ,辅以经静脉病人自控镇痛术和神经阻断术镇痛成功。患者治疗前后数字分级法、生存质量评估和卡诺夫斯基功能状态评分均明显改善 (均P <0 0 5 )。结论 晚期癌性疼痛患者居家镇痛治疗安全可靠、镇痛有效 ,患者生活质量明显提高。
Objective To observe and evaluate the analgesic effect of advanced cancer pain patients treated with home analgesia. Methods Fifty-two patients with pathologically confirmed advanced cancer were selected. The three-step analgesic principle of WHO was used as the guide. Analgesic drugs were mainly used in the home, supplemented by other anesthesia techniques and psychological counseling for comprehensive analgesic therapy. Analgesia using digital grading, quality of life assessment and assessment of Kanofsky functional status score. Results A total of 512 patients were withdrawn from the hospital in 3 cases. Four hundred and seventy-nine patients were treated with analgesia and the effective rate was 97.1%. Twelve patients with refractory pain were treated with intravenous patient-controlled analgesia and nerve blockade. Before and after treatment, the digital grading, quality of life assessment and Kanofsky functional status scores were significantly improved (all P <0 05). Conclusions The treatment of home pain in patients with advanced cancer pain is safe and reliable, analgesia is effective and the quality of life of patients is significantly improved.