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作者对6例血管免疫母细胞淋巴结病患者的淋巴结HE染色病理切片进行观察,发现其基本病理特征为小血管显著增生,以免疫母细胞为主的多种免疫细胞浸润,伴有细胞间及小血管壁有无定型嗜酸性物质沉积。其组织化学染色PAS及派若宁均阳性。免疫组织化学染色:4例免疫母细胞内IgG、IgM阳性,5例Kappa、Lambda染色阳性。这说明本病是一种活跃的免疫反应,而不是真正的肿瘤。有3例其细胞内风疹病毒抗原阳性,表明某些血管免疫母细胞淋巴结病与风疹病毒有密切关系。
The authors observed 6 cases of angioimmunoblastic lymph node disease in patients with HE staining of pathological sections were observed and found that the basic pathological features of small blood vessels significantly proliferate to immune cells dominated a variety of immune cells with cell-to-cell and small Blood vessel wall with or without eosinophilic deposition. The histochemical staining PAS and Pyridium were positive. Immunohistochemical staining: Immunoglobulin IgG, IgM were positive in 4 cases, Kappa was 5 cases, Lambda staining was positive. This shows that the disease is an active immune response, not a real tumor. 3 cases of intracellular rubella virus antigen positive, indicating that some vascular immunoblastic lymphadenopathy and rubella virus are closely related.