多发性骨髓瘤 (ＭＭ)是浆细胞的恶性肿瘤 ,其产生的大量单克隆免疫球蛋白血症是引起临床症状 (如高粘滞血症 )及肾功能损伤的主要原因之一。目前治疗多采用化疗 ,但化疗仅对瘤细胞有效 ,而对瘤细胞分泌的病理性球蛋白无效 ,我们采用先进行血浆置换 (ＰＥ)尽快清除体内的病理性 Multiple myeloma (MM) is a malignant neoplasm of plasma cells and produces a large amount of monoclonal immunoglobulinuria which is one of the main causes of clinical symptoms (such as hyperviscosity) and renal damage. At present, the treatment is more chemotherapy, but the chemotherapy is only effective for the tumor cells, but the pathological globulin secreted by the tumor cells is ineffective. We use the first plasma exchange (PE) to remove the pathological