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目的探讨原发性脾脏肿瘤的诊断和治疗。方法回顾分析1985年至2004年收治的24例原发性脾脏肿瘤的临床资料。结果24例中良性脾肿瘤10例,恶性脾肿瘤14例。B超检出率为95.8%(23/24),CT检出率为95.5%(21/22)。良性脾肿瘤10例中8例行开腹脾脏切除术,2例行腹腔镜下脾脏切除术;14例恶性脾脏肿瘤中13例行脾切除术(其中联合脏器切除4例),1例行肿瘤活检术。恶性脾肿瘤术后给以化疗、放疗等综合治疗。14例恶性肿瘤中获随访12例(随访率85.7%),其中1年内死亡5例,存活5年以上5例,2例术后1年尚在化疗中。结论原发性脾脏肿瘤的诊断主要依靠临床表现结合影像检查,外科根治手术结合综合治疗是提高脾脏肿瘤生存率的主要手段。
Objective To investigate the diagnosis and treatment of primary spleen tumors. Methods The clinical data of 24 patients with primary spleen tumors admitted from 1985 to 2004 were retrospectively analyzed. Results Of the 24 cases, 10 were benign splenic tumors and 14 were malignant splenic tumors. The detection rate of B ultrasound was 95.8% (23/24), and the detection rate of CT was 95.5% (21/22). Of the 10 benign splenic tumors, 8 underwent open laparoscopic splenectomy and 2 underwent laparoscopic splenectomy. Among the 14 patients with malignant spleen tumors, 13 underwent splenectomy (including 4 combined with resection of organs) and 1 Tumor biopsy. Malignant splenic tumor after chemotherapy, radiotherapy and other comprehensive treatment. Among 14 malignant tumors, 12 patients were followed up (85.7%), including 5 deaths in one year, 5 cases surviving for 5 years and 2 cases in 1 year after chemotherapy. Conclusion The diagnosis of primary splenic tumors mainly depends on clinical manifestations and imaging. Surgical radical surgery combined with comprehensive treatment is the main means to improve the survival rate of the spleen.