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目的观察单硝酸异山梨酯联合银杏叶片对不稳定型心绞痛的疗效。方法将70例不稳定型心绞痛患者随机分为治疗组和对照组,治疗组给予单硝酸异山梨酯片和银杏叶片口服,对照组给予拜阿司斯匹林肠溶片口服,疗程4周。观察用药前后患者症状、心电图改变,检测心功能指标,记录药物的不良反应。结果治疗组总有效率94.4%,对照组总有效率70.6%。治疗组疗效明显高于对照组。两组病人的每搏量(SV)、心排血量(CO)、左室射血分数(LEVF)值均较治疗前提高,治疗组SV、CO提高更为明显。两组均无明显不良反应。结论单硝酸异山梨酯联合银杏叶片治疗不稳定心绞痛疗效显著。
Objective To observe the effect of isosorbide mononitrate combined with ginkgo leaf on unstable angina pectoris. Methods Seventy patients with unstable angina pectoris were randomly divided into treatment group and control group. The treatment group was given isosorbide mononitrate tablets and ginkgo leaf tablets orally. The control group was given orally aspirin aspirin tablets orally for 4 weeks. Observed before and after treatment of patients with symptoms, ECG changes, detection of cardiac function indicators, record adverse drug reactions. Results The total effective rate was 94.4% in the treatment group and 70.6% in the control group. The treatment group was significantly higher than the control group. The stroke volume (SV), cardiac output (CO), and left ventricular ejection fraction (LEVF) in both groups were significantly higher than those before treatment, and SV and CO increased more significantly in the two groups. No significant adverse reactions in both groups. Conclusion Isosorbide mononitrate combined with ginkgo leaf for the treatment of unstable angina has a significant effect.