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目的:监测嗜铬细胞瘤(Pheo)患者立其丁试验血糖浓度变化的情况,了解可能导致低血糖的相关因素。使手术患者能更充分做好各项准备工作,安全度过围手术期,避免产生不良后果。方法:对22例行立其丁试验的经手术病理证实为嗜铬细胞瘤患者作回顾性分析,设立24例也做立其丁试验的其它病因所致的高血压患者为对照组;生化法测定丙氨酸氨基转移酶(A LT)、天门冬氨酸氨基转移酶(A ST)及血糖和糖化血红蛋白(H bA1c)。结果:嗜铬细胞瘤组有8例出现低血糖症而对照组仅有1例,两者差异有显著性(P<0.01);Pheo患者病程中收缩压(SB P)、舒张压(D B P)、肝功能(A LT、A ST)及H bA1C低血糖组与非低血糖组比较,差异有显著性(P<0.05)。年龄、体重指数(B M I)和试验前空腹血糖两组比较差异无显著性(P>0.05)。结论:嗜铬细胞瘤患者行立其丁试验易出现低血糖症;导致低血糖症的协同因素较多;嗜铬细胞瘤患者术前应常规行立其丁试验以间接了解术前术后患者血糖变化情况以便安全度过围手术期。
OBJECTIVE: To monitor changes in blood glucose levels in patients with pheo-pital and to examine the underlying causes of hypoglycaemia. Surgery patients to be able to do a better job of all the preparatory work, safely perioperative period, to avoid adverse consequences. Methods: A retrospective analysis was performed on 22 cases of pethidine-proven surgically and pathologically confirmed pheochromocytoma patients. Hypertensive patients with other causes of setting up their own small-for-small test were also included as control group. Biochemical methods Alanine aminotransferase (A LT), aspartate aminotransferase (A ST) and blood glucose and glycosylated hemoglobin (HbA1c) were determined. Results: In the group of pheochromocytoma, there were 8 cases of hypoglycemia and 1 case of control group, the difference was significant (P <0.01). SBP, DBP, , Liver function (A LT, A ST) and HbA1C hypoglycemia group compared with non-hypoglycemia group, the difference was significant (P <0.05). Age, body mass index (BMI) and fasting blood glucose before the two groups showed no significant difference (P> 0.05). CONCLUSIONS: Patients with pheochromocytoma are prone to have hypoglycemia in the setting-up trial, and there are many synergistic factors that cause hypoglycemia. Patients with pheochromocytoma should be routinely given their own statins before surgery to gain an understanding of preoperative and postoperative patients Blood glucose changes in order to safely perioperative period.