为提高头孢菌素菌渣的厌氧消化利用率,采用碱解与超声波破碎联合处理方法对头孢菌素菌渣进行细胞破壁,并通过正交实验和单因素实验研究pH值、含水率、声能密度和反应时间对破壁效果的影响。结果表明,最佳处理条件为:pH值为11.5、含水率为94%、声能密度为2 W/mL、反应时间为30 min,处理后SCOD溶解率为265.26%,总氮溶解率为155.28%,破壁效果明显。 In order to improve the rate of anaerobic digestion and utilization of cephalosporin bacteria residue, the cell wall of cephalosporin bacteria residue was treated by alkaline hydrolysis and ultrasonic disintegration. The effects of pH value, water content, Effect of Acoustic Energy Density and Reaction Time on the Breaking Effect. The results showed that the optimal treatment conditions were as follows: the pH value was 11.5, the water content was 94%, the acoustic energy density was 2 W / mL, the reaction time was 30 min, the SCOD dissolution rate was 265.26% and the total nitrogen dissolution rate was 155.28 %, Broken effect is obvious.