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目的:研究观察门诊使用硝苯地平缓释片与倍他乐克及单独使用硝苯地平缓释片治疗老年性高血压病的疗效,寻求最佳治疗方案。方法:对我院门诊2009年2月—2010年12月采用药物治疗的42例老年高血压患者进行回顾性分析,将患者随机分为两组,每组21例,一组使用硝苯地平缓释片进行治疗,为对照组;另一组使用倍他乐克联合硝苯地平缓释片进行治疗为观察组,连续治疗4周后进行疗效、副作用、复发率及患者满意率的比较。并将两组临床数据进行统计学分析。结果:观察组患者显效率为71.4%,总有效率为95.2%;较对照组的显效率28.6%,总有效率76.2%有明显优势,在副作用、复发率及患者满意率等方面比较观察组均有明显优势,经统计学分析,平均P=0.026<0.05。结论:倍他乐克联合硝苯地平缓释片在临床治疗老年高血压的疗效较单纯使用硝苯地平缓释片有明显优势,适于门诊患者的推广使用。
OBJECTIVE: To study the curative effect of nifedipine sustained-release tablets and metoprolol and nifedipine sustained-release tablets in the treatment of senile essential hypertension in outpatients, and to find the best treatment plan. Methods: A retrospective analysis was performed on 42 elderly patients with hypertension treated in our hospital from February 2009 to December 2010. The patients were randomly divided into two groups, 21 patients in each group. One group was treated with nifedipine The other group was treated with metoprolol combined with nifedipine sustained-release tablets for the observation group. The curative effect, side effects, recurrence rate and satisfaction rate of patients were compared after 4 weeks continuous treatment. And two sets of clinical data for statistical analysis. Results: The effective rate was 71.4% in the observation group and the total effective rate was 95.2%. Compared with the control group, the markedly effective rate was 28.6% and the total effective rate was 76.2%. There were obvious advantages in the side effects, recurrence rate and patient satisfaction rate Have obvious advantages, the statistical analysis, the average P = 0.026 <0.05. Conclusion: Betaloc combined with nifedipine sustained-release tablets in clinical treatment of elderly patients with hypertension than the simple use of nifedipine sustained-release tablets have obvious advantages, suitable for out-patient use.