论文部分内容阅读
目的对１００例肺癌，６８例肺炎，７２例健康人的血清血管紧张素转换酶活性的评价，并对肺癌患者化疗前后ＳＡＣＥ活性变化进行了对比观察。方法用紫外线分光光度测定血清中血管紧张素转换酶。结果肺癌患者的血清血管紧张素转换酶活性明显低于肺炎组及健康组织（Ｐ＜０．０１），肺癌患者经化疗后ＳＡＣＥ活性增高（Ｐ＜０．０１）。结论血清中血管紧张素活性的测定，对肺癌予后的估价及肺部阴影的鉴别诊断可能有一定帮助。
Objective To evaluate the activity of serum angiotensin-converting enzyme in 100 cases of lung cancer, 68 cases of pneumonia, and 72 cases of healthy people, and observe the change of SACE activity before and after chemotherapy in patients with lung cancer. Methods Ultraviolet spectrophotometry was used to measure angiotensin converting enzyme in serum. Results The activity of serum angiotensin-converting enzyme in lung cancer patients was significantly lower than that in pneumonia and healthy tissues (P<0.01). The activity of SACE in lung cancer patients increased after chemotherapy (P<0.01). Conclusion The determination of angiotensin activity in serum may be helpful for the evaluation of lung cancer postmortem and the differential diagnosis of pulmonary shadow.