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目的地屈孕酮治疗先兆流产的临床疗效,总结临床经验。方法将2010年3月至2013年1月本科收治的117例先兆流产患者随机分为对照组与试验组,其中对照组肌肉注射黄体酮,试验组口服地屈孕酮,记录并作回顾性分析。结果治疗后试验组孕8、9、10、11周血清孕酮以及有效率、流产率、胎儿畸形率、不良反应等方面与对照组相比差异无统计学意义(P>0.05)。结论地屈孕酮治疗先兆流产安全、有效,能够起到与黄体酮相同的效果,值得推广。
Objectives Progesterone treatment of threatened abortion clinical efficacy, summarize clinical experience. Methods From March 2010 to January 2013, 117 patients with threatened abortion were randomly divided into control group and trial group. The control group received intramuscular injection of progesterone and the test group received oral progesterone orally. The data were recorded and retrospectively analyzed . Results After treatment, serum progesterone, effective rate, abortion rate, fetal malformation rate and adverse reactions in experimental group at 8, 9, 10 and 11 weeks of pregnancy were not significantly different from those in control group (P> 0.05). Conclusions Dydrogesterone is safe and effective in the treatment of threatened abortion, which can play the same effect as progesterone and is worth promoting.