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目的 观察全身热化疗治疗晚期恶性肿瘤尤其是耐药人群的临床疗效。方法 用ET SPACETM全身热疗系统使患者均衡地、逐渐地加热至 4 1 5℃～ 4 1 8℃ ,恒温期维持 6 0min ,针对不同疾病分别选用顺铂 (DDP)、氟尿嘧啶 (5 FU)、奥沙利铂 (L OHP)、表阿霉素 (EIP)、环磷酰胺 (CTX)等药物于恒温期使用。结果 2 6 7%达PR ,PR +SD为 85 6 % ,伴癌性疼痛的患者治疗后疼痛消失或缓解率为 85 7% (6 / 7) ,既往化疗失败的患者有 6 6 7%经热化疗后仍取得较好疗效。结论 全身热疗加化疗治疗晚期恶性肿瘤有较好的临床疗效。
Objective To observe the clinical efficacy of systemic hyperthermia in the treatment of advanced malignant tumors, especially drug-resistant populations. Methods ET SPACETM systemic hyperthermia system was used to warm up patients gradually and gradually to 4 1 5 ° C to 4 1 8 ° C for 60 minutes. DDP, 5 FU, Oxaliplatin (L OHP), epirubicin (EIP), cyclophosphamide (CTX) and other drugs used at constant temperature. Results 26.7% of the patients had PR and 85.8% of patients had PR + SD. The pain disappeared or remission rate was 85.7% (6/7) in patients with cancer pain, and 67.7% of those who had previous chemotherapy failure After hyperthermia still achieved good effect. Conclusion The whole body hyperthermia plus chemotherapy for the treatment of advanced malignant tumors have a better clinical effect.