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本品系白色结晶性粉末,无臭,味微苦。对湿、热,光不稳定,易溶于水,微溶于甲醇,几乎不溶于乙醇,乙醚,氯仿和苯。其水溶液pH为5～6,适于作注射剂使用。阿司匹林在临床上应用已有八十余年历史,因疗效确切,毒性较低,在国内外受到普遍重视,至今仍为常用的解热镇痛药。但由于它在水中的溶解度小,不宜作注射剂使用;在口服时,易在胃酸的作用下分解成水杨酸,而致刺激胃壁,使有些患者不能耐受。为了减少其副作用,提高疗效,扩大应用范围,国外进行了各方面的研究。在1970年法国研制成了阿司匹林和赖氨酸的复盐,在水中具有很好的溶解度,
This product is white crystalline powder, odorless, slightly bitter taste. Wet, heat, light instability, soluble in water, slightly soluble in methanol, almost insoluble in ethanol, ether, chloroform and benzene. The aqueous solution of pH 5 ~ 6, suitable for injection. Aspirin has been used clinically for more than 80 years and has been widely used both at home and abroad due to its curative effect and low toxicity. It is still commonly used as antipyretic and analgesic drugs. However, due to its low solubility in water, should not be used as an injection; when taken orally, it is easy to decompose into salicylic acid under the action of stomach acid, which will stimulate the stomach wall and make some patients intolerant. In order to reduce its side effects, improve efficacy, expand the scope of application, all aspects of foreign research. In 1970 France has developed a double salt of aspirin and lysine, has good solubility in water,