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The cycle of G-protein activation and deactivation is a key in the signaling pathway of GPCRs (G protein coupled receptors). GTPase-activating proteins (GAPs) regulate heterotrimeric G proteins by increasing the rates at which the (subunits hydrolyze bound GTP to GDP. RGSs (regulators of G protein signaling) is a novel family and, in most cases, implicated in accelerating the hydrolysis of GTP. The opioid receptors are all seven serpentine transmembrane receptors coupled with G proteins Gi, Go, even Gs. Adenylate cyclase (AC) is a
The cycle of G-protein activation and deactivation is a key in the signaling pathway of GPCRs (G protein coupled receptors). GTPase-activating proteins (GAPs) regulate heterotrimeric G proteins by increasing the rates at which the (subunits hydrolyze bound GTP to GDP RGSs (regulators of G protein signaling) is a novel family and, in most cases, implicated in accelerating the hydrolysis of GTP. The opioid receptors are all seven serpentine transmembrane receptors coupled with G proteins Gi, Go, even Gs. Adenylate cyclase AC) is a