C反应蛋白(CRP)是人类急性期反应蛋白,可独立预测健康人群及心血管病患者未来心血管事件的发生。研究表明CRP可促进动脉粥样硬化的形成。肝X受体(LXR)活化配体是细胞核激素受体超家族成员,在多种动物模型中可抑制巨噬细胞炎症基因表达及减轻动脉粥样硬化病变。已知两种合成的LX C-reactive protein (CRP), a human acute-phase response protein, independently predicts future cardiovascular events in healthy people and patients with cardiovascular disease. Research shows that CRP can promote the formation of atherosclerosis. Liver X receptor (LXR) activating ligands are members of the nuclear hormone receptor superfamily, which inhibits macrophage inflammatory gene expression and attenuates atherosclerotic lesions in a variety of animal models. Two synthetic LXs are known