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Crohn’s 病(CD)累及口或卵巢者极为少见,而同一患者口和卵巢同时受累尚未有过报告。作者报告1例 Crohn’s 病回结肠炎,经活检证实其病变累及口和卵巢。26岁黑人女患者,因间歇性腹绞痛约1年,于1971年首次就诊,诊断卵巢囊肿收住院。行剖腹探查时,发现回肠末段及盲肠 Crohn’s 病,伴多处粘连,炎症并波及腹膜、肠和右侧子宫附件。行阑尾切除及右卵巢活检。镜检见卵巢被颗粒层细胞分隔为数个小囊,浆膜表面下方散布非干酪性上皮样肉芽肿,特殊染色未找到抗酸杆菌和真菌。出院前 X 线检查发现回肠末段6英寸处 Crohn’s 病,其近端明显狭窄,近端小肠扩张。1973年5月发生小肠梗阻,每天服柳氮磺胺吡啶2g,强的松15mg,情况尚好。同年9月因小肠梗阻再次住院。X 线检查见远端回肠多处狭窄,
Crohn’s disease (CD) involving the mouth or ovary is extremely rare, while the same patient mouth and ovarian involvement have not been reported. The authors report 1 Crohn’s disease colitis, biopsy confirmed the lesions involving the mouth and ovary. 26-year-old black female patient, due to intermittent abdominal cramps for about 1 year, first visit in 1971, diagnosis of ovarian cysts in hospital. During a laparotomy, Crohn’s disease in the distal ileum and caecum, with multiple adhesions, inflammation, and peritoneal, intestinal, and right uterine appendages were found. Appendectomy and right ovary biopsy. Microscopically, the ovaries were separated by granular cells into several small vesicles. Non-caseous epithelioid granulomas were spread beneath the serosal surface. Acid-fast bacilli and fungi were not found in special staining. Pre-discharge X-ray examination revealed a Crohn’s disease 6 inches distal to the ileum with a marked stenosis in the proximal and a dilatation in the proximal small bowel. Small intestinal obstruction occurred in May 1973, daily serving sulfasalazine 2g, prednisone 15mg, the situation is still good. The same year in September due to small bowel obstruction again hospitalized. X-ray examination showed distal ileum multiple stenosis,