目的　探讨不同药物治疗方案对同一种疾病所产生的经济效果。方法　运用药物经济学成本 -效果分析法对幽门螺旋杆菌 (Hp)感染的消化性溃疡的 3种治疗方案进行分析评价。结果　无论是从成本 -效果比分析 (C/E) ,还是从增长的成本 -效果比分析 (△C/△E) ,均得出B方案为治疗Hp阳性的消化性溃疡的最佳方案。结论　运用药物经济学理论指导临床合理用药 ,可使有限的卫生资源得到合理配置 Objective To explore the economic effects of different drug treatment programs on the same disease. Methods Three methods of treatment of peptic ulcer with Helicobacter pylori (Hp) infection were analyzed and evaluated by cost-effectiveness analysis method in pharmacoeconomics. Results The best regimen for treating Hp-positive peptic ulcer was B regimen, both from cost-effectiveness analysis (C / E) and from increasing cost-benefit ratio analysis (△ C / △ E). Conclusion The use of pharmacoeconomic theory to guide the clinical rational use of drugs, limited health resources can be rational allocation