论文部分内容阅读
本文对急性髓系白血病(AML)首次完全缓解(CR)后再强化疗与强化疗合并自体骨髓移植的效果进行随机对比研究,结果如下。 病人与方法 病人是从1966例AML经DAT(柔红霉素、阿糖胞苷、硫鸟嘌呤)或DAE(柔红霉素、阿糖胞苷、足叶乙甙)方案化疗获得完全缓解者中选出381例,再给予氨苯丫啶100mg/m~2、阿糖胞苷200mg/m~2、足叶乙甙100mg/m~2均用5天强化,然后全部病人采集自体骨髓,单个核细胞数不低于1.0×10~8/kg,随机分为自体骨髓移植组(BMT组)190例,男89例,女101例,
This article randomized and compared the effects of first-time complete remission (CR) after acute myeloid leukemia (AML) with strong chemotherapy and autologous bone marrow transplantation. The results are as follows. Patients and Methods Patients were completely regressed from 1966 AML patients treated with DAT (daunorubicin, cytarabine, thioguanine) or DAE (daunorubicin, cytarabine, etoposide) chemotherapy A total of 381 patients were selected and 100 mg/m~2 of ampicillin was given, cytarabine 200 mg/m~2, and 100 mg/m~2 of acetochlor were all boosted for 5 days. All patients were then collected from autologous bone marrow. The number of mononuclear cells was not less than 1.0×10~8/kg, which was randomly divided into 190 cases of autologous bone marrow transplantation (BMT) group, 89 males and 101 females.