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目的:探讨在治疗晚期贲门癌中采用奥沙利铂+替吉奥同步三维放疗治疗的临床疗效及毒副反应。方法:调研时间:2014年3月～2016年3月,调研对象:我院收治的60例中晚期贲门癌患者,随机分为经单纯放疗的对照组及观察组(采用奥沙利铂+替吉奥及三维适形放疗治疗),30例/组;比较两种不同治疗方案干预贲门癌患者的临床效果+毒副反应。结果:经同步放化疗,观察组患者总稳定率、缓解率、进展率等均优于对照组,P<0.05。同时观察组总不良反应率为20.00%,对照组总不良反应率为13.33%,观察组发生不良反应率高于对照组,差异显著。结论:在治疗中晚期贲门癌中,使用奥沙利铂联合替吉奥同步三维放疗治疗疾病,临床效果较单纯放疗效果好,值得医师推广。
Objective: To investigate the clinical efficacy and side effects of oxaliplatin and tirgilux in the treatment of advanced cardia cancer. Methods: The study period from March 2014 to March 2016, the subjects of study: 60 patients with advanced cardia cancer treated in our hospital were randomly divided into control group and observation group (using oxaliplatin + Gio and three-dimensional conformal radiotherapy), 30 cases / group. The clinical effect and toxicity of two different treatment regimens in patients with cardiac cancer were compared. Results: After concurrent chemoradiotherapy, the total stable rate, remission rate and progression rate in the observation group were better than those in the control group (P <0.05). At the same time, the total adverse reaction rate in the observation group was 20.00%, the total adverse reaction rate in the control group was 13.33%, and the adverse reaction rate in the observation group was higher than that in the control group, with significant difference. Conclusion: In the treatment of advanced cardia cancer, the use of oxaliplatin in combination with TIGO synchronous three-dimensional radiotherapy for the treatment of disease has a better clinical effect than radiotherapy alone and is worthy of promotion by a doctor.