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本文报道用左旋咪唑治疗11例类风湿性关节炎的临床疗效和免疫学观察。11例中男3例、女8例,年龄19～69岁,病程1～33年。类风湿因子阳性者9例,阴性者2例。用药方法:A组2例每14天中连续3天服用左旋咪唑150毫克/天,B组7例每天服150毫克,C组2例在开始1～5个月,每14天中连服3天,然后改为每天服用(150毫克/天)。结果:A组1例,B组4例,C组1例有效。2例中断治疗,其中1例是因为左旋咪唑引起过敏性皮疹,另1例是由于停用肾上腺皮质激素后,出现了肾上腺皮质功能减退的表现。6例治程达3～11个月,皆取得一定疗效,疼痛减轻,每天关节僵直的时间缩短,功能改善,主觉好转,抗炎药物用量减少,例如某些患者从原用强的松8毫
This article reports the clinical efficacy and immunological observation of levamisole in treating 11 cases of rheumatoid arthritis. 11 cases of 3 males and 8 females, aged 19 to 69 years, duration of 1 to 33 years. Rheumatoid factor positive in 9 cases, negative in 2 cases. Methods of treatment: A group of 2 patients every 3 days for 3 days taking levamisole 150 mg / day, B group 7 cases taking 150 mg per day, C group 2 cases in the first 1 to 5 months, every 14 days with service 3 Day, then change to daily (150 mg / day). Results: 1 patient in group A, 4 patients in group B and 1 patient in group C were effective. Two patients discontinued treatment, of which 1 was levamisole-induced allergic rash and 1 was due to cortical hypofunction after corticosteroid withdrawal. 6 cases of treatment up to 3 to 11 months, have achieved a certain effect, reduce pain, shorten the time of joint stiffness every day, functional improvement, the main improvement, reduce the amount of anti-inflammatory drugs, such as some patients from prednisone 8 Milli