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使用氦氖激光、Ｎｄ∶ＹＡＧ 倍频脉冲激光和铜蒸气激光，以不同剂量对洛法他汀产生菌Ｌ１１０９ 进行诱变照射，同时对激光修复作用进行探讨。结果表明，被照菌株产洛法能力有不同程度提高。氦氖激光照射最高提高２３－２ ％ ，Ｎｄ∶ＹＡＧ 倍频脉冲激光照射最高提高２０－８％ 。铜蒸气激光照射提高６－３ ％ 。将菌株紫外线辐射后再以低剂量氦氖激光照射，获得一株高产优质新菌种Ｌ２１０１ ，产洛法能力提高３０ ％ 以上，遗传性能稳定。
Using He-Ne laser, Nd:YAG frequency-doubling pulsed laser and copper vapor laser, different doses of lovastatin-producing strain L1109 were mutated and irradiated, meanwhile laser repair effect was discussed. The results showed that the capacity of the irradiated strains increased to varying degrees. He-Ne laser irradiation up to 23-2%, Nd: YAG multiplier pulse laser irradiation up to 20-8%. Copper vapor laser irradiation increased by 6-3%. The strain UV radiation and then low-dose He-Ne laser irradiation, to obtain a high-yielding new strain of high-quality L 2 101, yield increased productivity by 30%, genetic performance and stability.