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目的了解巴音郭楞蒙古自治州乙肝疫苗接种有效率,为进一步提高预防和控制HBV感染提供依据。方法采用分层随机抽样的方法抽取2012-2015年出生儿童,以接种证为依据,完成乙肝疫苗全程免疫,采集血样,用ELISA法检测抗-HBs。结果城镇儿童乙肝表面抗体阳性率为76.41%,农村儿童乙肝表面抗体阳性率为63.40%;2012-2013年出生儿童乙肝表面抗体阳性率为56.71%,2014-2015年出生儿童乙肝表面抗体阳性率为81.19%;汉族儿童乙肝表面抗体阳性率为73.05%;少数民族儿童乙肝表面抗体阳性率为63.78%。结论接种疫苗是预防乙肝的一种有效方式,随着时间的过去,乙肝疫苗在个体内产生的抗体水平有所下降,所以,进一步加强新生儿及学龄前儿童乙肝疫苗规范接种、复种工作是预防和控制HBV感染的有效手段。
Objective To understand the efficiency of hepatitis B vaccination in Bayingolin Mongolia Autonomous Prefecture and provide evidence for further prevention and control of HBV infection. Methods Children born from 2012 to 2015 were drawn by stratified random sampling method. Based on the vaccination certificate, whole-blood immunization of hepatitis B vaccine was completed, blood samples were taken and anti-HBs were detected by ELISA. Results The positive rate of HBsAg in urban children was 76.41%, the positive rate of HBsAg in rural children was 63.40%, the positive rate of HBsAg was 56.71% in children born in 2012-2013, and the positive rate of HBsAg in children born in 2014-2015 was 81.19% respectively; the positive rate of HBsAg in Han children was 73.05%; the positive rate of HBsAg in ethnic minority children was 63.78%. Conclusion Vaccination is an effective way to prevent hepatitis B. Over time, the level of antibody produced by hepatitis B vaccine in the individual has declined. Therefore, to further strengthen the standard vaccination of hepatitis B vaccine in newborns and preschool children, vaccination is the prevention And effective means of controlling HBV infection.